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Are BOM cost optimization questions on-topic?

Are BOM/PCB assembly cost cost optimization questions on-topic here? 

I can see how chasing down specific parts, prices and vendors ought to be off-topic, so I don't mean outright shopping/second source recommendations. 

But I rather mean a design review of the schematic as whole, to suggest cheaper designs or removal of unnecessary components. Or replacing unique component values with others already present on the board in order to reduce pick & place rigging times. Double-sided vs single-sided SMD mounting and so on. 

Obviously electronic designers will benefit by learning such tips & tricks from each other. But also from getting a design review by a professional assembly contractor, since they consider entirely different things than an EE.

Also such cost optimizations might quickly turn very technical. Take for example all the things to consider when replacing relays with MOSFET drivers, or when changing battery chemistry etc.